Fighting Hospital Acquired Infections | Trelleborg Sealing Solutions

Fighting Hospital Acquired Infections

Exploring methods of combining silicone tubing with APIs

Fighting Hospital Acquired Infections

All elements of a sealing system must work together as a team


Healthcare-Associated Infections are a major, yet often preventable threat to patient safety. Since they can have a significant impact on the survival rate of patients undergoing medical procedures and treatment, the minimization of such infections is an important focus globally.

While there has been some success in decreasing hospital-acquired infections, they still remain a significant issue. Particularly catheter-associated infections are difficult to prevent due to their inherent positioning both inside and outside the body. 

Catheter tubes are usually made of silicone and although the material is biocompatible and bio-stabile, it is not immune to bacterial colonization. There are some techniques that can reduce bacterial colonization:

Applying antibiotic Active Pharmaceutical Ingredient (API) coatings to silicone catheters by spraying or dipping

Addition of antibiotic APIs to raw silicone

Impregnation of vulcanized silicone with antibiotic API through immersion

This whitepaper outlines these three techniques and presents test results proving the effectiveness of the immersion impregnation method in combining an API with silicone tubing to prevent catheter-associated infections.

Download this whitepaper to learn more about combining silicone tubing with APIs to reduce hospital-acquired infections

Note: Our whitepapers are only available to website members.